![]() Now you’ve created a rocky, improvised staircase. ![]() This is where you slice it in half horizontally with your laser and grapple the top off, pulling it toward you. ![]() The problem is that the first rock is much taller than the succeeding ones. Look around and you’ll find a series of rocks leading to another area. These paths are easy enough to spot on the first level. Tiny & Big always has a set path or two for you to progress to the end of the level on, but there is always room for making your own way (and ruining the set ones) with your arsenal. In all cases, Tiny survives by way of his tool set: a grappling hook, an infinite supply of rockets, and a laser beam that can cut through almost anything. When a pillar and boulder isn’t standing in Tiny’s way, Big is there to toss one directly at Tiny. Tiny is pretty good at jumping, but that’s not enough to get through the crypts, canyons, and desert plains of his world. Big likes to throw things at Tiny, using telekinesis. Wanting to be the one who wears the magical underpants on his head, Tiny chases after the awfully mean bully Big. Tiny & Big is a prime example that there are still plenty of fun, untapped ideas that just wouldn’t work in 2D. Maybe, it’s once again up to indie developers to show the big leagues that there is still much to be accomplished in the 3D platformer. Before Nintendo and Ubisoft reimagined their flagship platformers in 2D, indie developers were paying tribute to their childhood favorites. Somehow the tides reversed: The 2D platformers of yesteryear came in vogue over the past decade, while 3D platformers largely fell out of favor. Tiny & Big: Grandpa’s Leftovers (PC, Mac) Like other indie games, it runs out ideas before its half-way point … an hour into the game. But, in contrast to other indie games, this one has confident, fully realized visuals, mechanics, and design. It has cured my uncle’s bleeding ulcers, renewed my aging pug’s libido, and given me enough money to fill up my parent’s swimming pool full of tapioca and swim in it.Įxcept, Tiny & Big is yet another example of a bite-sized indie game that doesn’t quite reach its potential. Here is where I tell you that Tiny & Big is a revelation and a game changer, rewriting every rule this medium has been built upon. But what is being truly independent without risk and ambition? It’s like these indie creators exist in a world where only singles and EPs exist making an LP is just too ambitious and risky. ![]() From where I sit, it seems like they are rebelling against investing time in developing a strong visual style and fleshing out mechanics. Indie game designers often like to depict themselves as rebels, talking out against the modern weapon war and race for realistic graphics being put on by the major game publishers of the world. ![]()
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![]() Please don't hesitate to contact us at support at audulus dot com if you have any questions or need help. ▶ Recommended hardware: 4th Generation iPad or later. Polyphonic/Monophonic signal converters.Math expression module - 34 operation expression language.Mathematical Modules: Addition, Multiplication, Subtraction, Sine, Modulo.Virtual Analog Oscillator (4 classic waveforms).Timing mode - figure out which nodes are using the most CPU!.iCloud support - effortlessly sync patches between Mac and iPad.Universal Modulation - modulate any knob.Audiobus support! - Runs as both an Input and Effect.Virtual MIDI – control Audulus from your favorite MIDI app.Round-trip workflow with Audulus for Mac.Unlimited Undo - full history stored in a patch.32-bit floating-point signal processing.Patch Browser - quickly flip through your patches.MIDI control - use your control surface or MIDI keyboard.Fluid Vector Interface - smooth animated interaction.▶ Visit the Audulus Forum for exciting FREE user-created patches! ◀ "The biggidy bomb coolest most super tech-nerd fun times soft synth I've bought in recent times!" - Mac App Store Australia review It has one of the best UIs I've ever used." - USA Mac App Store review ![]() "Audulus is fantastic, a thinking man's synth." - UK App Store review It can be likened to Turbosynth, the early Digidesign program, but it can also be compared to music programming environments like Max, Csound, and SuperCollider. "Anybody into synthesis should check out Audulus on the iPad. Audulus is a modular music synthesis and processing app for iPhone, iPad, and Mac. "Audulus 3 out and is stunning!" - Richard Devine, ▶ Winner of Electronic Musician Magazine Editor's Choice Award, 2017 Audulus's user interface is clean, simple, and easy to learn, allowing you to focus on sound - now made easier than ever with nearly 100 built-in Eurorack-style modules. All with low latency real-time processing suitable for live performance. With Audulus, you can build synthesizers, design new sounds, or process audio. ![]() ![]() There is evidence that mutation in somatic cells causes cancer, genetic disorders and many other degenerative disorders including arthritis and connective tissue disorders, hepatic disorders, neurodegenerative disorders, cardiovascular disorders, diabetes, chronic inflammation, ageing etc. Many diverse environmental, industrial, dietary and natural chemicals are capable of inducing mutation and genotoxic effects. These agents produce a variety of lesions in DNA including strand break, base damage and dimerisation of bases. These include, physical agents like Ultra Violet (UV) and X-rays which cause the deletion of nucleotide. Mutagens: The substances which can induce mutations are known as mutagens. The chemical and physical factors that induce mutation are called mutagens and those that reduce their mutagenicity are called antimutagens ( Venitt and Parry, 1984). Mutations cause permanent alteration in DNA structure, which have been implicated in the etiopathology of cancer and other degenerative diseases. In general, mutations are detrimental because in most cases they lead to defects in cellular functions. Mutation occurs spontaneously or may be induced by several physical, chemical or biological agents. This change may be expressed, for example as change in the structure of a protein which alters or abolishes its enzymatic properties. Mutation: Mutation refers to heritable change in nucleotide sequence or number occurring due to alteration in the sequence of the code in a gene due to change, removal or insertion of one or more bases in a gene resulting in an altered gene product ( Hartl et al., 1994). In this review promise of these natural antimutagens has been focused upon. A large number of experimental reports have begun to appear in the scientific literature, wherein increasingly more natural antimutagens have been identified, isolated and found to possess significant mutation chemoprevention properties. Hence, research work related to the discovery, characterization and use of antimutagenic agents is receiving considerable attention. Moreover, there is an increasing awareness that certain naturally occurring substances in plants and other source have protective effects against environmental mutagens or carcinogens and also endogenous mutagens. Prevention of cancer and other mutation related diseases can be pursued by avoiding exposure to recognized carcinogens or mutagens, by favoring the intake of protective factors and by fortifying physiological defense mechanism. Environmental pollution is associated with increased risk of cancer. The group of chemicals that cause cancer in man and animals are collectively referred to as carcinogens. Many of these substances elicit, apart from their antimutagenic and anticarcinogenic properties, additional beneficial effects such as activation of the immune system and/or protection against cardiovascular diseases ( Middleton and Kandaswami, 1993). ![]() These bioactive compounds belong to a variety of different chemical groups such as phenolics, pigments, allylsulfides, glucosinolates, tannins, anthocyans, flavonoids, phytosterols, protease inhibitors and phytoestrogens. There are continued efforts all over the world to explore the rich biodiversity of edible as well as medicinal plants and other edible non-toxic plants in pursuit of the most effective phytoantimutagens. Numerous studies have been carried out in last four decades in order to identify compounds that might protect humans against DNA damage and its consequences. Such chemicals that reduce the mutagenicity of physical and chemical mutagens are referred to as antimutagens ( Mitscher et al., 1986). Since, the mutagens are involved in the initiation and promotion of several human diseases, including cancer, the significance of novel bioactive phytocompounds in counteracting these pro-mutagenic and carcinogenic effects is now gaining credence. There is increasing evidence that mutation in somatic cells are not only involved in the carcinogenesis but can also cause genetic disorders like atherosclerosis, heart diseases and several other degenerative disorders ( De Flora et al., 1996). A plethora of synthetic and natural substances, apart from various genotoxic physical and biological agents are known to act as mutagenic, co-carcinogenic and/or carcinogenic agents. Mutations are the cause of innate metabolic defects in cellular systems, triggering morbidity and mortality in living organisms. ![]() ![]() Kratom is a plant-based powder, pill, or tea marketed as a miracle herb that will alleviate pain, anxiety, and even opioid addiction. If this can save just one other mother’s baby, then it will not have been in vain.” He spoke of his dreams of having an impactful career of helping others. He was an empath and cared deeply for people. He was silly and goofy and loved theater, computers, and cars. ![]() Nathan Minns mother, Shanon, describes her son as having “an infectious smile and a belly laugh that would make anyone around him light up. It’s frequently sold without labeling or packaging, so no mention of strength, ingredients, contaminants, or even dosing measurements.” “People have no idea what they’re getting. Unbelievably, it is completely unregulated.” the attorney representing the family, Brantley White, said. “This drug has dangerous opioid-like tendencies, and it is sold in unlimited quantities. The company makes no mention of the hazardous nature of Kratom nor that the FDA has urged sellers to destroy the drug. ![]() In addition, the lawsuit says that businesses like Green Gorilla misrepresent the safety of Kratom by saying the dangerous product is a safe, natural remedy. The family of 19-year-old Nathan Minns alleges that despite warnings from the FDA, Green Gorilla sold Kratom in an unmarked bag without any warnings or dosage restrictions to the unsuspecting teen. LUBBOCK, Texas - The family of a Lubbock teen has filed a wrongful death lawsuit against Lubbock, Texas smoke and vape shop Green Gorilla after his life was tragically cut short by the “herbal supplement” Kratom. ![]() ![]() Some studies have shown that short fluctuations in irradiance and cloud over play an important role in distribution networks of low voltage with high penetration of PV. These variations also depend on the functioning of the whole PV system, PV modules, inverter, filters, control mechanisms etc. This is because incoming power fluctuations can be offset by slight changes in rotor speed.įor PVs, solar radiation varies randomly, causing a change in the system power flow and hence variations in the output voltage. The use of converters provides the possibility of reducing the dynamic voltage fluctuations. Wind turbulence together with the turbine dynamic itself creates power variations in the region of 0.01–10 Hz. Moreover, it usually includes a smooth control to avoid switching transients that occur when capacitor banks are included. When the wind turbine system includes power converters connected to the grid, the inverter control usually includes a loop to control the voltage level and reactive power. A relation of two or three times generates a low impact, provided that the system is equipped with capacitor banks to compensate the reactive power. For induction generator systems connected directly to the network, fixed speed systems depend primarily on the X/ R relation of the network. The impact on the voltage level of the wind turbines depends on the generator type. When it comes to large turbines in a wind farm operating at the same time, significant impacts may occur in the system. In the case of wind power, wind is unstable in nature, which causes fluctuations in the output power of wind turbines. DG produced by solar energy and wind are two clear examples of systems with output powers that vary randomly. (8.16) Δ U = R P + X Q U P C C + j P X + Q R U PCCĪs can be deduced, variations in the active power or reactive power injected into the network cause voltage fluctuations in the grid. Hence, modern-day inverters are capable of operating at a power factor less than unity leading or lagging for the voltage support at the point of common coupling. ![]() Inverter controlled reactive power mechanism can help alleviate the voltage issues locally. The issue of reverse power flow occurs from voltage imbalance in the feeder owing to an imbalance between PV generation and demand in the feeder. The impact of voltage variation is more profound in low voltage feeders compared to the medium voltage feeders as the value of X/R is higher in the latter case. When PV output increases rapidly in a weak system due to the movement of cloud, the voltage at the point of common coupling increases and vice versa. Network characteristics also influence the power quality issue as voltage rise happens when there is a high impedance between the PV output and the nearest pole-top transformer. “Voltage fluctuation” arising from PV systems can be classified into voltage imbalance and voltage rise, leading to reverse power flow. On the other hand, sustained high voltages have unfavorable impacts on the life span of network equipment. System-wide brownouts may occur due to extended under-voltages in the network arising from very high PV output drop. This can also activate excessive automated tap changing on distribution transformers, which affects the life span of the transformer and increase annual maintenance costs. Voltage fluctuations are the main power quality issue faced by the PV-based hybrid systems owing to a short-term solar irradiance variation. Taskin Jamal, Sayedus Salehin, in Hybrid Renewable Energy Systems and Microgrids, 2021 5.3.1.1 Voltage impact Hybrid renewable energy sources power systems There can be overlap of load modification variations that can result in wider limit bands. Some countries have tighter limits for voltage variations. The allowed variation is ☑0% for most countries. These can be evaluated as per the emission limits guidelines for fluctuating loads in medium-voltage and high-voltage networks. The wind turbine on/off sequence produces the voltage fluctuations. Depending on the voltage level the angle varies from 30 to 85 degrees for medium- and high-voltage networks, respectively. The flicker coefficient and its specifications are either given by manufacturers or can be determined. This is influenced by averaging annual wind speed, the point of turbine installation, and the phase of short circuit impedance. Flicker coefficient is the indicator of severity of fluctuation. Voltage fluctuation occurs due to the output power variations depending upon the source type, generator characteristics, and impedance of the network. Hari Om Gupta, in Power Quality in Modern Power Systems, 2021 3.3.1 Voltage fluctuations ![]() Power quality problems with renewable energy integration ![]() ![]() ![]() ![]() In the Apple menu, select System PreferencesĢ. To find a free proxy server, search for “free proxy server” on Google and add the desired country to your search query. With this, Spotify will not send you ads. Similar to using a VPN, a proxy helps give the illusion that you’re in a country where Spotify is not available. Change the proxy settings to stop Spotify adsĬhange the proxy settings to stop Spotify ads.When it comes to experiencing Spotify with no ads on your Mac, you have a few options that you can try. Clario lets you encrypt your data, so you can make it seem like you’re logging in from a different location.Īside from being able to have a more enjoyable experience using Spotify, Clario helps you stay safe while you’re on public connections, anonymize your online activities, and protect your data from being stolen. With Clario, you can use its VPN features across all platforms from Android, iOS, to Mac. Select a different VPN location, such as Switzerland or Singapore.Here’s how to block Spotify ads with a VPN: However, that with a VPN enabled, you might experience a slower internet connection and might experience a higher data usage. With a Virtual Private Network (VPN), you can listen to ads from other countries where the amount of ads on Spotify might be less. To accomplish this, you can set your device’s location to a country with significantly fewer audio ads like Switzerland or Singapore. However, it’s possible to have a much better experience with its ads by hearing less of them. Unfortunately, Spotify has a policy against using ad blockers. How to block ads on Spotify for iOS and Android ![]() ![]() ![]() Similarly, in the construction games played in the past, the player decided what kind of resources to produce, or provided them to the residents through various methods such as purchases and transactions, but here, there is no other way but to build the land. Although active, it is very difficult to "arrange troops" and you can only let it go. ![]() ![]() In "Deisim VR" or in games like God Simulator, the shape of the houses and villages is not determined by the player. In general construction games, the player decides where to place the house. For example, as long as there is water, men and women holding fishing rods and rowing boats will automatically go fishing as long as there are mines, mining pits will slowly develop as long as there are trees, there will be simple warehouses for hoarding wood.Īlthough Tutu is cute, God himself can't do anything about it Because the game has added AI, players cannot control which piece of land civilization will be generated on, nor can they control the progress of civilization. It seems that the operation space is very large, but in fact, the player can have little impact on the land they build. The above mentioned various operations and god skills. In addition to basic infrastructure, what exactly is this game playing? Infrastructure handle, mentality Waterloo As for the other destructive skills, the small ones caused the villagers to flee, while the large ones caused the people to lose their lives. If you place a wrong ground or want to redecorate, you can use nothingness to directly restore this ground to its original appearance. In addition to infidels, players have to prevent UFOs from taking away your people from time to time, like this:Īs for destruction, destruction includes nothingness, tornadoes, fires, and thunderstorms. In fact, there are methods such as fire roasting or flooding, but in general it is a bit creepy. At this time, players need to continue to pay attention to maintenance and eliminate abnormalities. After it is turned on, there will be cardinals who will continue to teach among the various villages, and the red-stained villages will take the initiative to attack and pollute other villages. In the settings, choose whether to turn on the pagan mode. With the expansion of the village, the materials they need will become more advanced and require More elaborate arrangements and strategies.įrom another perspective, players also need to maintain "psychology". They can only directly or indirectly give them the materials they need through their needs. As a god, players cannot directly interfere with human behavior. This is similar to most construction games, but the interesting thing is that the initial village of humans is called "Eden", which automatically derives various villages and cultures on various terrains. At the same time, animals, minerals, etc. Players can press X to call out the menu, and they can select various terrains such as plains, forests, cherry blossom forests, water surfaces, snow, deserts, volcanoes, etc. This identity player can mainly do three things, creating, maintaining and destroying. In "Deisim VR", the player plays the role of a creator. ![]() It is worth noting that this kind of game mode that has not received much attention in the country, but is highly rated in the history of the game, has a VR version-"Deisim VR". The top of the game itself is a relatively high evaluation of this game, the reason can be said later. Afterwards, apart from the sequel "Black and White 2" and its imitations, no more god simulators appeared, and in China, this type of game did not receive much attention, and even Baidu even had an entry. ![]() ![]() ![]() Unfortunately, there are no good obesity statistics going back that far, so we’re left simply to wonder whether this “diet” even worked at all.Īs an interesting footnote, old-school advertising is still boosting Lucky Strike sales, after a fashion. By 1950, nearly half of American women were smoking. And even after the campaign finally ended, the social destigmatization of women smoking was almost complete. instead of a sweet” to appease candy makers, but continued pitching cigarettes as a way to curb overeating. While other cigarette brands had begun targeting women too, Lucky Strike’s unparalleled rise to cigarette stardom implies that their “cigarettes for weight loss” ad campaign had a fair amount of impact. The percentage of women smokers in America jumped from 5-6% (1924) to 12-16% of women (1929), an increase of at least four million new women smokers. ![]() Almost overnight, Lucky Strike cigarettes became the #1 cigarette brand in the United States, their sales increasing 300% in just one year. In 1928, the American Tobacco Company began running ads for their “Lucky Strike” cigarettes, specifically targeting women with the tagline “Reach for a Lucky instead of a sweet.” Often featuring thin, attractive women juxtaposed against obese ones, these advertisements pitched cigarettes as a way of guarding against “unhealthy” snacking that might lead to unattractive weight gain. Courtesy of the Stanford School of Medicine’s SRITA website. But in the 1920s, tobacco companies started going after women, too. Nearly all of these ads were targeting men, over 50% of whom were already smokers. Celebrity endorsements were mixed with “throat doctors” making spurious medical claims. The tobacco companies, worried that widespread discussion of the obvious might turn people off the habit, turned to marketing to win back the hearts and minds and lungs of the public. Even if there wasn’t definitive scientific evidence, it was apparent that something about smoking was sickening and killing smokers. Just look at the language people were using: the first use of the phrase “coffin nails” was in 1888, and the phrase “smoker’s cough” was coined in 1898. By the late 1800s, public opinion was souring on cigarettes. RARE BIG-TWIN BOBBER WITH BIG MOTOR AND BIG POWER. 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![]() ![]() There's some good, some bad and some ugly. Now that Reason+ has been out for over year, I've done an updated review to look at how that first year has played out. So I'd actually rate Reason+ higher than Reason, especially if you're using it as plugin. However, the overall package presented with Reason+ is pretty great, when you factor in all of the instruments effects, utilities, etc. But now that it's been out for over a year and still has not seen any significant improvements (while its peer DAWs have been improving), I think the core score for Reason 12 is more like a 6/10. When Reason 12 was first released, I gave it an 7/10. This gets you access to a ton of sounds and flexibility for a very affordable price. However, you can also run Reason 12 inside of another DAW as a super-powerful instrument and effects suite. It lacks many of the features that have long been standard among its competitors, and there is no clear indication that this will be changing. That said, Reason's core architecture is outdated. I think that this aspect makes Reason especially well suited for guitar players or folks that are into modular synthesis. There's something about it that feels more like an instrument than a piece of recording software. ![]() I also think that Reason is probably the most fun and inspiring DAW. Song I've made in Reason have been streamed hundreds of thousands of time, placed on TV Shows and Netflix Documentaries, and broadcast on NPR. Reason 12 will be the core of your Reason+ experience, so it's worth thinking about whether Reason is a good DAW for you. I've already done a full in-depth Reason 12 review here. ![]() ✅ Click here to check the price of Reason+ Is Reason a Good DAW? ![]() ![]() Just because two things often occur together does not mean that they will necessarily always occur together.Others simply couldn’t follow what was going on, struggling to follow the steps in reasoning between “people,” “train,” and “time.” But I loved it.ĭespite the outrage, the professor was demonstrating some of the most fundamental principles of thinking: Many would accuse the professor of making shit up to humiliate them and give them poor grades. I don’t think I’ve ever seen so many pissed off twenty-year-olds as I did in that classroom each week. Pretty much everyone in the class would answer “yes” and then become infuriated when the professor told us the correct answer was no-just because trains always arrive when there are many passengers does not mean that many passengers will always result in a train arriving. Is it necessarily true that a train will arrive soon?” You arrive at the station and see many passengers waiting on the platform. “Every time a train arrives at the station, there are many passengers on the platform. Each morning, we’d all come into class to find a question like this on the board: ![]() I needed to take an elective from the humanities department, and not wanting to get sucked into a seminar on “Romantic literature of the 1840s” or whatever, I went for the least humanities-sounding thing I could find on the list: a philosophy course called “Logic and Reasoning.” It probably ended up being the most valuable course I ever took in my life.įrom day one, I loved my logic course. That happened to me in my sophomore year. ![]() I mean that most of the courses you take will never be all that relevant to the rest of your life.īut then, every once in a while, often by accident, you stumble into a course that is hugely impactful on your life. That’s not because the professors are bad or the coursework is pointless (although sometimes that is definitely the case). I’m going to be honest: most courses you take in university aren’t worth a whole lot. ![]() |
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